Scholars International Conference and Exhibition on
Pharmaceutics and Drug Delivery Systems
THEME: "Enlightening the recent advances in Drug Delivery Research and Nanomedicine"
23-24 Sep 2024 
Village Hotel Changi, Singapore THEME: "Enlightening the recent advances in Drug Delivery Research and Nanomedicine"
23-24 Sep 2024
Village Hotel Changi, Singapore 
Lomonosov Moscow State Univercity, Russia
Hybrid Nanosystems Based on Silver Nanoparticles with Cholesteric Ligands: biomedicine application
Gromova Yana Andreevna graduated from the Faculty of Chemistry, Lomonosov Moscow State University (Moscow, Russia, 2014) specialising in analytical chemistry. Then (2014-2018 years) she studied fulltime postgraduate studies at the Faculty of Chemistry, Lomonosov Moscow State University (physical chemistry). She defended my PhD in 2019 (physical chemistry). Now she is a researcher at the Department of Chemical Kinetics, Laboratory of Low Temperature Chemistry (Faculty of Chemistry, Lomonosov Moscow State University) headed by prof., doc. of sciences in physical chemistry Shabatina Tatiana Igorevna.
The aim of our research is the preparation of new functional materials the practical applications of which are quite extensive. These are supramolecular aggregates based on liquid crystal optically active ligands of cholesterol, thiocholesterol including silver nanoparticles. Our research takes into account modern trends in science aimed at the creation of new materials with prospects for use in biomedical applications as new carriers of drugs of different nature and pharmaceutical purpose. Fixation of functionalized silver nanoparticles on the surface of inert and biocompatible spherical silica gel leads to the formation of new carriers for drugs. The pronounced antibacterial properties of silver nanoparticles combined with interesting physicochemical properties of liquid crystal ligands (cholesterol, thiocholesterol, 7-aminocholesterol) lead to new supramolecular aggregates possessing a spatially ordered structure with improved physicochemical properties. Such hybrid systems have proven efficiency as adsorption materials, as well as prospects for application as new drug carriers. Our interest concerns steroid hormones such as estradiol and dehydroepiandrosterone, which are structurally similar with respect to the surface of the studied hybrid systems.
